About Paul E. Zollinger MD PhD


State University, Leiden MD, Medical degree with honours (cum laude) 1990
Leyenburg Hospital, The Hague Orthopaedic Surgery 1996-1999
Red Cross Hospital & Burns Center, Beverwijk Surgery 1994-1995
Sophia Children's Hospital at Erasmus University, Rotterdam Paediatric Orthopaedics 1998
Free University, Amsterdam Vitamin C for prevention of CRPS-I in traumatology and orthopaedic surgery (ISBN 978-90-8890-009-9) 2008


Surgical Center
  • Rivierenland Ziekenhuis | Tiel, The Netherlands

Society memberships

Additional Society Memberships
  • Netherlands Orthopaedic Association (NOV)

  • Netherlands Orthopaedic Trauma Society (NVOT)

  • European Orthopaedic Research Society (EORS)

  • swiss orthopaedics (formerly known as Schweizerische Gesellschaft für Orthopädie und Traumatologie [SGOT/SSOT])

  • Société Internationale de Chirurgie Orthopédique et de Traumatologie (SICOT)


Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures: a randomized trial. Paul E. Zollinger, Wim E. Tuinebreijer, Robert W. Kreis and Roelf S. Breederveld. The Lancet, Vol 354, 11th December 1999, 2025-8.

Prenatal ultrasonographic diagnosis of posteromedial bowing of the leg: two case reports. P.E. Zollinger, M.W. Wessels, J.W. Wladimiroff and A.F.M. Diepstraten. Ultrasound in Obstetrics and Gynecology 2000 Feb; 15(2): 150-3.

Quantification of first tarsometatarsal joint stiffnes in hallux valgus patients. F.W.M. Faber, P.E. Zollinger, G.J. Kleinrensink, L. Damen, P.G.H. Mulder, C.J. Snijders and J.A.N. Verhaar. Clinical Biomechanics 16 (2001) 714-6.

Can vitamin C prevent Complex Regional Pain Syndrome in patients with wrist fractures? A randomized, controlled, multicenter dose-response study. P.E. Zollinger, W.E. Tuinebreijer, R.S. Breederveld and R.W. Kreis. The Journal of Bone and Joint Surgery, July 2007, Vol. 89-A No.7: 1424-31.

Late reconstruction of a traumatic trapeziometacarpal dislocation with a semi-constrained prosthesis; a case report. Paul E. Zollinger. European Journal of Trauma and Emergency Surgery, 2007; 33:648-50.

Clinical outcome of cementless semi-constrained trapeziometacarpal joint arthroplasty, and possible effect of vitamin C on the occurrence of complex regional pain syndrome. Paul E. Zollinger, Maarten L. Ellis, Halil Ünal, Wim E. Tuinebreijer. Acta Orthopaedica Belgica 2008; 74: 317-22.

Clinical results of 40 consecutive basal thumb prostheses and no CRPS type I after vitamin C prophylaxis. Paul E. Zollinger, Halil Ünal, Maarten L. Ellis and Wim E. Tuinebreijer. The Open Orthopaedics Journal, 2010; 4: 62-66.

No higher risk of CRPS after external fixation of distal radial fractures – subgroup analysis under randomised vitamin C prophylaxis. Paul E. Zollinger, Robert W. Kreis, Hub G. van der Meulen, Maarten van der Elst, Roelf S. Breederveld and Wim E. Tuinebreijer. The Open Orthopaedics Journal, 2010; 4: 71-75.

Evidence based guidelines for complex regional pain syndrome type 1. Perez RS, Zollinger PE, Dijkstra PU, Thomassen-Holgersom IL, Zuurmond WW, Rosenbrand KC, Geertzen JH; CRPS I task force. BMC Neurol 2010 March 31; 10: 20.

The Administration of Vitamin C in Prevention of CRPS-I After Distal Radial Fractures and Hand Surgery - A Review of Two RCTs and One Observational Prospective Study. Paul E. Zollinger. The Open Conference Proceedings Journal, 2011, 2, 1-4 (25 January, 2011).


Lower incidence of reflex sympathetic dystrophy in wrist fractures after administration of vitamin C, on the 5th June at European Federation of National Associations of Orthopaedics and Traumatology, 4th EFORT Congress, 3-8 June 1999, Brussels, Belgium.

Prophylaxe der Dystrophie mit Ascorbinsäure in der Versammlung für Orthopädie und Traumatologie der Helioskliniken, am 15.en September 2000, Erfurt, Thüringen, Deutschland.

'The role of vitamin C in prevention of CRPS type I after wrist fractures' and 'First experiences with the Roseland CMC-I prosthesis' at the Surgical-Medical Research Institute, on the 11th July 2003, University of Alberta, Edmonton, Canada.

Clinical outcome of 34 implantations of a cementless semi-constrained trapeziometacarpal joint prosthesis - An observational prospective cohort study with vitamin C prophylaxis, on the 26th April at 17th annual meeting of the European Orthopaedic Research Society (EORS), 24-26 April 2008, Madrid, Spain.

Less CRPS type I in hand surgery after oral vitamin C, at the 6th Congress of the European Federation of IASP Chapters (EFIC) - Pain in Europe VI, 9-12th September 2009, Lisbon, Portugal.

The administration of vitamin C in prevention of CRPS-I in traumatology and orthopaedic surgery - A meta-analysis, on the 4th of February 2010 at the 2nd International Conference on Drug Discovery & Therapy, 1-4th February 2010, Dubai, UAE.

Prospective cohort study of 50 trapeziometacarpal joint replacements with the Roseland prosthesis after vitamin C prophylaxis, on the 7th of September 2011 at the XXV Triennial World Congress of SICOT 6-9th September 2011, Prague, Czech Republic.

Trapeziometacarpal joint replacement with an uncemented prosthesis: prospective clinical results under vitamin C prophylaxis on the 28th of June at the 72. Jahreskongress der Schweizerischen Gesellschaft für Orthopädie und Traumatologie SGOT/SSOT 27-29th June 2012, Basel, Switzerland.

Outcome assessment of 58 basal thumb joint replacements with additional vitamin C at the 20th Annual Meeting of the European Orthopaedic Research Society (EORS), 26-28 September 2012, Amsterdam, The Netherlands.

A rotating hinged knee prosthesis for revision surgery and primary cases; 14 years of experience and Forgotten Joint Score, SICOT Orthopaedic World Congress, 8-10th September 2016, Rome, Italy.

Contact Information

Ziekenhuis Rivierenland Pres. Kennedylaan 1 Tiel, NLD 4002 WP View map Phone 0(031)344674217 Fax 0(031)344632903

Barbara Polikliniek Elisabethdreef 4 Culemborg, NLD 4101 KL Phone 0(031)345565600 Fax 0(031)344632903

Other staff in my practice

Maarten L. Ellis
Chantal T.H. van Hal
Halil Ünal

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